Physical Therapists News

Understanding SMA Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy.1 In this paper, the authors elucidate a mechanism of the motor neuron degeneration that occurs in SMA. Specifically, the authors found that dysfunction of Stasimon, a protein of…

2019 was a year of significant progress in our understanding of SMA and how to best address it – clinically and otherwise. Below is a roundup of some of the final SMA data shared in late 2019. Understanding SMA The classical complement pathway mediates microglia-dependent remodeling of spinal motor circuits…

With patients that are diagnosed with SMA, they can have a hard time controlling their neck and trunk, which makes it more difficult to be independent with chair mobility, such as ascending and descending ramps, as well as assisting with transfers. When first starting these exercises, it is…

Regulators continue to review SMA drugs and consider policies related to newborn screening while new data emerge related to the mechanisms underlying the disease, as well as those concerning management and treatment.  Here is a roundup of some of the latest news and research related to SMA. Understanding SMA…

Working with a patient with SMA is not all that different from working with any other patient. Your plan of care advances and changes while working with the patient and making observations as you see fit to the patient’s overall wellbeing. To get Michael positioned for the assisted…

While the biggest news this week may be the success of the drug risdiplam in improving motor function in a late stage clinical trial on patients with SMA types 2 and 3,1 other important data on SMA have also been published in recent weeks. Below is a roundup of new…

With a patient like Michael, who has SMA, it can be a challenge to continue growing their treatment plan by presenting new exercises that help them reach their goals.  Often times we resort to starting a new exercise and modifying it depending on Michael’s performance. Although I know…

Summer has closed with new data and news on SMA coming to the fore. Much of the research on SMA published in recent weeks has focused on how to best treat the disease, and some new debate has emerged surrounding the relative advantages of Zolgensma versus Spinraza. At the same…

Students must perform multiple clinical rotations before they graduate PT or PTA school. When students come into our outpatient clinic, they are exposed to a wide variety of diagnosis. One that always baffles them is SMA. In most cases. SMA is briefly taught about in school, because physical therapy…

Summer is closing with an abundance of new data on SMA. Studies aimed at understanding the disease process continue to provide information on its underlying mechanisms. At the same time, careful investigations of therapeutics are highlighting the potential of these interventions and identifying critical questions for future research, as well…