Featured Physical Therapist Articles on HCP
Orthopedics and Bracing Considerations for SMA
SMA provides myriad challenges to multiple people on the caregiving team. As a prosthetist and orthotist, there are a few observations I have made over the years in terms of bracing considerations for SMA. The first big question relates to whether to brace or not,...
New Way of Restoring SMN Protein Levels by Targeting RNA Holds Promise, Study Says
A new way of restoring potentially adequate levels of survival motor neuron (SMN) — the protein missing in spinal muscular atrophy (SMA) — uses small molecules that target the structure of an intermediate player in this protein's production. The study on this...
Nerve Cell Function Impacted When Movement is Limited, Mouse Study Suggests
Neurological health depends as much on signals sent by the body's leg muscles to the brain as it does on those sent from the brain to the muscles, according to a recent study. These results offer new clues as to why patients with neurological diseases such as spinal...
#CureSMA2018 – Exicure’s SNA Formulation of Nusinersen Raises SMN Protein Levels with Lesser Toxicity, Mouse Study Reports
Exicure’s gene c prolongs survival, increases the amount of SMN proteins, and shows limited toxicity in a mouse model of the disease, study data show. The investigational compound is a spherical nucleic acid (SNA) formulation of nusinersen, the active substance in...
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