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The other day, my friends and I were talking about our mantras for the upcoming year. I usually start thinking about mine sometime in December, so this conversation was par for the course — something about the darkest month of the year makes me yearn for the optimism…

UNITY Screen, a noninvasive prenatal blood test, can provide an accurate personalized risk assessment for hereditary diseases such as spinal muscular atrophy (SMA) in fetuses, according to a recent study. Offered by BillionToOne in the U.S., the single-gene noninvasive prenatal test (sgNIPT) included in UNITY Screen…

The elevated production of the cell-death-related protein c-Fos was closely linked to the death of motor neurons in two mouse models of spinal muscular atrophy (SMA), a study showed. Motor neurons are the muscle-controlling nerve cells that are lost in people with SMA. Although c-Fos didn’t directly cause…

I listened to 78,978 minutes of music and podcasts in 2022. Thanks to the popular feature Spotify Wrapped, I and millions of users can look at a summary of our listening habits each year, for better or worse. Some may find my avid consumption of pop albums…

This year has been unprecedentedly good in terms of media. From season four of “Stranger Things” to the delightfully campy “Our Flag Means Death,” I’ve had no shortage of things to binge. But the highlight has undoubtedly been the renewed interest in “Star Wars.” It started with the six-episode…

People with spinal muscular atrophy (SMA) types 2 or 3 who start treatment with Spinraza (nusinersen) and show less muscle damage on MRI scans are more likely to see motor function improvements, a new study reports. The finding “underscores the importance of early diagnosis and treatment to…

Last year, my brother and I plotted to round up our respective families for Thanksgiving. It was a daunting effort. Our family branches are scattered over three states, and, as usual, work schedules conflicted. Alas, thanks to some angel intervention and alignment of enough stars, we managed to come…

Without disease-modifying treatment (DMT), spinal muscular atrophy (SMA) carries high mortality rates and steep healthcare costs, a study in Hong Kong reported. Not surprisingly, the greatest loss of life and highest costs were observed in children with SMA type 1, one of this disease’s most severe forms…

My life flashed before my eyes. Or, to be more specific, all the meals I’ve eaten in my life flashed before my eyes. I’d determined with complete certainty that I was lactose intolerant. My symptoms aligned perfectly — namely, I experienced gastrointestinal issues after ingesting dairy products. I’d finally…

A new system that contains a gene-modulating therapy attached to an antibody that enables crossing into the nervous system improved survival outcomes in a mouse model of severe spinal muscular atrophy (SMA), a new study reports. The study, “Antibody-oligonucleotide conjugate achieves central nervous system delivery…