SBMA Seen to Affect Skeletal Muscles First, Not Motor Neurons

SBMA Seen to Affect Skeletal Muscles First, Not Motor Neurons

Although a disease of motor neurons, nerve cells of the spinal cord and brainstem, the earliest signs of spinal and bulbar muscular atrophy (SBMA) are in skeletal muscles, according to data from a mouse study. These findings suggest that changes in muscle strength and...
Benefits of Long Sitting Unsupported In a Patient With SMA

Benefits of Long Sitting Unsupported In a Patient With SMA

When working with a patient with SMA, you will most likely find that their sitting balance is not optimal while sitting unsupported, due to a lack of core strength. While every patient has different strengths and weaknesses, as well as abilities and disabilities, it...
Study Addresses Dilemmas Regarding Newborn Screening and SMA Treatment

Study Addresses Dilemmas Regarding Newborn Screening and SMA Treatment

As newborn screening for spinal muscular atrophy (SMA) becomes more common, ethical dilemmas will arise about the best treatment strategy for individuals with four copies of the SMN2 gene, a new study contends. The study, “Infants Diagnosed with Spinal Muscular...
Physical Therapy With An SMA Patient During The COVID-19 Pandemic

Physical Therapy With An SMA Patient During The COVID-19 Pandemic

With the pandemic occurring around us, there have been many changes for everyone in everyday life. Physical Therapy is an essential medical practice and has stayed open during this pandemic, but there have been changes made to protect us and our patients. We have...
Motor Gains and Safety with Zolgensma’s IT Use Continue, STRONG Data Show

Motor Gains and Safety with Zolgensma’s IT Use Continue, STRONG Data Show

Young children given a single injection of Zolgensma into the spinal canal continue to show gains in motor function and safety, new interim data from the STRONG trial in spinal muscular atrophy (SMA) type 2 patients up to age 5 show. These findings from the open-label...