Nephrolithiasis (Kidney Stones) in Spinal Muscular Atrophy

Nephrolithiasis (Kidney Stones) in Spinal Muscular Atrophy

Nephrolithiasis is not a classic or well-documented symptom of spinal muscular atrophy (SMA). Nonetheless, anecdotal reports from physicians, patients, and caregivers suggest that patients with SMA may suffer from kidney stones more frequently than an otherwise...
Spinal Muscular Atrophy: Chewing and Swallowing Problems

Spinal Muscular Atrophy: Chewing and Swallowing Problems

Patients with Spinal Muscular Atrophy (SMA) types 2 and 3 frequently report weakness of the muscles of mastication and bulbar impairment leading to chewing and swallowing issues.1 Patients with SMA type 1 have such significant bulbar weakness that precludes safe...
Spinal Muscular Atrophy: Pancreatic Dysfunction

Spinal Muscular Atrophy: Pancreatic Dysfunction

Traditionally, the pathology of Spinal Muscular Atrophy (SMA) was thought to be entirely confined to the anterior horn cells of the spinal cord.1 As more is known about the natural history of SMA, other cell types inside and outside the central nervous system appear...